Although a new software in the field, Pumas products have already been used in a variety of projects. Here is a list of publications, posters and presentations that used Pumas to perform modeling & simulation.
Rackauckas, Chris, Yingbo Ma, Andreas Noack, Vaibhav Dixit, Patrick Kofod Mogensen, Simon Byrne, Shubham Maddhashiya, et al. “Accelerated Predictive Healthcare Analytics with Pumas, a High Performance Pharmaceutical Modeling and Simulation Platform.” BioRxiv, November 30, 2020, 2020.11.28.402297. https://doi.org/10.1101/2020.11.28.402297 .
Rackauckas, Christopher Vincent, Vaibhav Dixit, Adam R. Gerlach, and Vijay Ivaturi. “Efficient Precision Dosing Under Estimated Uncertainties via Koopman Expectations of Bayesian Posteriors with Pumas.” *BioRxiv*, January 27, 2021, 2021.01.25.428134. https://doi.org/10.1101/2021.01.25.428134.
Pumas-NLMEPumas-OD
Ma, Yingbo, Shashi Gowda, Ranjan Anantharaman, Chris Laughman, Viral Shah, and Chris Rackauckas. “ModelingToolkit: A Composable Graph Transformation System For Equation-Based Modeling.” *ArXiv:2103.05244 [Cs]*, March 9, 2021. http://arxiv.org/abs/2103.05244.
Pumas-PBPKPumas-QsP
Rackauckas, C. “Generalizing Automatic Differentiation to Automatic Sparsity, Uncertainty, Stability, and Parallelism,” *Stochastic Lifestyle*, March 10, 2021. https://www.stochasticlifestyle.com/generalizing-automatic-differentiation-to-automatic-sparsity-uncertainty-stability-and-parallelism/.
Pumas-PBPKPumas-QsP
Kalaria, Shamir N., Michael Armahizer, Paul McCarthy, Neeraj Badjatia, Jogarao V. Gobburu, and Mathangi Gopalakrishnan. “A Prospective, Real-World, Clinical Pharmacokinetic Study to Inform Lacosamide Dosing in Critically Ill Patients Undergoing Continuous Venovenous Haemofiltration (PADRE-02).” *British Journal of Clinical Pharmacology* n/a, no. n/a. Accessed May 7, 2021.https://doi.org/10.1111/bcp.14858.
Pumas-NCAPumas-NLME
Pal, Avik, Yingbo Ma, Viral Shah, and Christopher Rackauckas. “Opening the Blackbox: Accelerating Neural Differential Equations by Regularizing Internal Solver Heuristics.” *ICML 2021*, May 9, 2021. http://arxiv.org/abs/2105.03918.
Pumas-DeepNLMEPumas-NLME
Strauss, Erik R., Elyes Dahmane, Miranda Judd, Dong Guo, Brittney Williams, Michael Meyer, James S. Gammie, et al. “A Pharmacokinetic and Pharmacodynamic Investigation of an ε-Aminocaproic Acid Regimen Designed for Cardiac Surgery With Cardiopulmonary Bypass.” *Journal of Cardiothoracic and Vascular Anesthesia*, July 21, 2020. https://doi.org/10.1053/j.jvca.2020.07.048.
Pumas-NLMEPumas-NCA
Miszta, Adam, Homa K. Ahmadzia, Naomi L. C. Luban, Shuhui Li, Dong Guo, Lori A. Holle, Jeffrey S. Berger, et al. “Application of a Plasmin Generation Assay to Define Pharmacodynamic Effects of Tranexamic Acid in Women Undergoing Cesarean Delivery.” *Journal of Thrombosis and Haemostasis* 19, no. 1 (2021): 221–32. https://doi.org/10.1111/jth.15114..
Pumas-NCAPumas-NLME
Dandekar, Raj, Vaibhav Dixit, Mohamed Tarek, Aslan Garcia-Valadez, and Chris Rackauckas. “Bayesian Neural Ordinary Differential Equations,” December 14, 2020. https://arxiv.org/abs/2012.07244v2..
Pumas-DeepNLME
Kalaria, Shamir N., Michael Armahizer, Paul McCarthy, Neeraj Badjatia, Jogarao V. Gobburu, and Mathangi Gopalakrishnan. “A Practice-Based, Clinical Pharmacokinetic Study to Inform Levetiracetam Dosing in Critically Ill Patients Undergoing Continuous Venovenous Hemofiltration (PADRE-01).” *Clinical and Translational Science* 13, no. 5 (September 2020): 950–59. https://doi.org/10.1111/cts.12782.
Pumas-NLMEPumas-NCA
Rackauckas, Chris, Yingbo Ma, Andreas Noack, Vaibhav Dixit, Patrick Kofod Mogensen, Simon Byrne, Shubham Maddhashiya, et al. “Accelerated Predictive Healthcare Analytics with Pumas, a High Performance Pharmaceutical Modeling and Simulation Platform.” *BioRxiv*, November 30, 2020, 2020.11.28.402297. https://doi.org/10.1101/2020.11.28.402297.
Pumas-NLMEPumas-NCAPumas-BEPumas-ODPumas-PBPK