October 1, 2026

Accelerated E-R Modeling for Extended-Release Buprenorphine for Opioid Use Disorder

Don't just take our word for it. Hear how an industry team used Pumas® to achieve more than 25x faster NLME model runtimes during a complex exposure-response analysis.

When database lock doesn't move, model execution matters.

Join Lauren Lohmer, PhD, and Celine Laffont, PhD from Indivior as they share their experience using Pumas to accelerate a large-scale exposure-response (E-R) modeling program evaluating extended-release buprenorphine (BUP-XR) in patients with opioid use disorder.

Faced with a complex integrated analysis spanning two clinical studies (N=989), increasing prevalence of fentanyl and polysubstance use, and demanding timelines, the team needed a faster way to develop, evaluate, and report NLME models across multiple efficacy endpoints.

In this customer-led webinar, you'll learn:

  • Why the team chose Pumas for a complex population PK and E-R modeling workflow
  • How they analyzed opioid use, opioid craving, and treatment retention using NLME and time-to-event methods
  • How model runtimes were reduced from days to hours, enabling a more efficient workflow and faster decision-making
  • How rapid generation of diagnostics, goodness-of-fit plots, and visual predictive checks streamlined reporting
  • Key scientific findings on buprenorphine exposure in patients with fentanyl and polysubstance use

Why Attend?

✅ Hear directly from an industry customer, not PumasAI

✅ Learn how tight modeling timelines were successfully managed

✅ See a real-world case study of accelerated NLME model development

✅ Discover how Pumas supported the execution of more than 700 model runs and enabled on-time delivery of results

Date: October 01, 2026, 11am ET 

Duration: 1 hour

Speakers: Lauren Lohmer, PhD (Indivior); Celine Laffont, PhD (Indivior); Andreas Noack, PhD (PumasAI)

Register here!

The best Pumas testimonial isn't from PumasAI. It's from the scientists who used it to deliver under real-world timelines.


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3500 South Dupont Highway
Suite GT-101
Dover, DE 19901
Email: info@pumas.ai
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Pumas-AI Inc.
3500 South Dupont Highway
Suite GT-101
Dover, DE 19901
Email: info@pumas.ai
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