Date: November 4-5, 2025

Location: PAGJa 2025, Campus Plaza Kyoto

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Nonlinear Mixed Effects Modeling Workflows using Pumas

This hands-on, two-day workshop is tailored for both beginners and those with some experience in clinical pharmacology data analytics. Dive into Pumas, a cutting-edge pharmacometric platform for modeling and simulation in drug development. Participants will explore workflows ranging from foundational concepts to advanced applications.

Key Highlights

• Sequential PKPD
• Clinical Trial Simulation
• Population Pharmacokinetics
• DeepNLME for Covariate Identification
• DeepNLME for Dynamical System Identification

PLUS: A sneak peek into DeepPumas — Where machine learning integrates with pharmacometrics

Objectives

This workshop provides a deep dive into Pumas, a powerful pharmacometric platform designed for modeling and simulation in drug development. Participants will gain hands-on experience and knowledge of the standard workflows in population pharmacokinetics (PK) and sequential PKPD modeling. Experts will guide attendees through various stages of model building, diagnostics, and data wrangling, with opportunities to explore specialized areas like absorption models, using non-Gaussian random effects.

Instructors

Vijay Ivaturi, PhD

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