Beyond Gaussian Random Effects

When: Tuesday March 30 2021, 9:30 AM - 10:30 AM Eastern Time (US)

Where: Online

Presenters: Mr. Mohamed Tarek, Scientist at Pumas-AI, Inc. and Dr. Andreas Noack, Director of Engineering Research at Pumas-AI, Inc.

In this webinar, we will go through an overview of the Laplace and first order methods commonly used in pharmacometrics to compute the marginal likelihood. We will show how these methods can be generalized to handle non-Gaussian random effects and then demonstrate how to define these non-Gaussian random effects in Pumas models and then perform maximum likelihood estimation. Fed up of defining random effect transformations? Always wanted to use fancier, more flexible, non-symmetric distributions for your random effects? This webinar is for you!

Check out the third webinar in the Pumas 2.0 feature series "Support for Non-Gaussian Random Effects Specification" for more information. Register now!